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Chloroprocaine

Chloroprocaine (2-Chloroprocaine) is a potent inhibitor of Na, K-ATPase activity with an IC50 of 13 mM. Chloroprocaine blocks peripheral nerve[1].

Product Specifications

CAS Number

[133-16-4]

Product Name Alternative

2-Chloroprocaine

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Na+/K+ ATPase

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/chloroprocaine.html

Solubility

10 mM in DMSO

Smiles

CCN(CCOC(C1=C(Cl)C=C(N)C=C1)=O)CC

Molecular Formula

C13H19ClN2O2

Molecular Weight

270.76

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]H Kutchai, et al. Inhibition of the Na, K-ATPase of Canine Renal Medulla by Several Local Anesthetics. Pharmacol Res. 2001 Apr;43 (4) :399-403.|[2]Chloroprocaine HCl Injection.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Launched

Curated Selection

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