ST166 (free acid)
ST166 free acid is a inhibitor of formation of the PhoP-DNA complex with the IC50 values of 18 and 24 μM against PhoP and MtrAC binding with DNA, respectively. ST166 free acid shows antibacterial activity against Macrobacterium marinum[1].
Product Specifications
CAS Number
50580-23-9
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/st166-free-base.html
Smiles
O=S(CC1CSSCC(CS(=O)(O)=O)SS1)(O)=O
Molecular Formula
C6H12O6S6
Molecular Weight
372.55
References & Citations
[1]Su HL, Lai SJ, et al. Structure-guided identification and characterization of potent inhibitors targeting PhoP and MtrA to combat mycobacteria. Comput Struct Biotechnol J. 2024;23:1477-1488. Published 2024 Apr 3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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