Naftazone

Naftazone is a naphthoquinone derivative, it can be used for the research of venous insufciency. Naftazone protects blood vessels, increases venous tonicity and capillary resistance, and improves lymphatic and venous circulation[1][2].

Product Specifications

CAS Number

[15687-37-3]

UNSPSC

12352005

Hazard Statement

H315, H319, H320

Target

Endogenous Metabolite; iGluR; mGluR

Type

Reference compound

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/naftazone.html

Purity

99.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C2=CC=CC=C2C=C/C1=N\NC(N)=O

Molecular Formula

C11H9N3O2

Molecular Weight

215.21

Precautions

H315, H319, H320

References & Citations

[1]Mattei C, et al. Naftazone reduces glutamate cerebro spinal fluid levels in rats and glutamate release from mouse cerebellum synaptosomes. Neurosci Lett. 1999 Aug 27;271 (3) :183-6. |[2]McGregor L, et al. Effect of naftazone on in vivo platelet function in the rat. Platelets. 1999;10 (1) :66-70.