CDK2-IN-32
CDK2-IN-32 (Compound 5g) is a selective CDK2 inhibitor with an IC50 of 0.21 μM. CDK2-IN-32 shows cytotoxicity against Vero cells with an IC50 of 28.52 μM[1].
Product Specifications
UNSPSC
12352005
Target
Apoptosis; CDK
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk2-in-32.html
Smiles
ClC1=CC(Cl)=CC(C(CN2C=NC3=C(N=CN=C23)NCC4=CC=CO4)=O)=C1
Molecular Formula
C18H13Cl2N5O2
Molecular Weight
402.23
References & Citations
[1]Shah A, et al. Novel purine derivatives as selective CDK2 inhibitors with potential anticancer activities: Design, synthesis and biological evaluation. Bioorg Chem. 2024 Sep 24;153:107841.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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