NAD+
NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.
Product Specifications
CAS Number
53-84-9
Product Name Alternative
β-DPN; β-NAD; β-Nicotinamide Adenine Dinucleotide
UNSPSC
12352005
Hazard Statement
H303, H371
Target
Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/NAD_addition_.html
Purity
99.99
Solubility
H2O : 29.17 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O[C@@H]1[C@H](O)[C@@H](COP(OP(OC[C@@H](O[C@H]([C@@H]2O)N3C=NC4=C3N=CN=C4N)[C@H]2O)(O)=O)([O-])=O)O[C@H]1[N+]5=CC(C(N)=O)=CC=C5
Molecular Formula
C21H27N7O14P2
Molecular Weight
663.43
Precautions
H303, H371
References & Citations
[1]Viollet, B., et al., Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond), 2012. 122 (6) : p. 253-70.|[2]Brandt, U., Energy converting NADH:quinone oxidoreductase (complex I) . Annu Rev Biochem, 2006. 75: p. 69-92.|[3]Kussmaul, L. and J. Hirst, The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc Natl Acad Sci U S A, 2006. 103 (20) : p. 7607-12.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 2
Isoform
Human Endogenous Metabolite
Available Sizes
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