NAD+

NAD+ is a coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage.

Product Specifications

CAS Number

[53-84-9]

Product Name Alternative

β-DPN; β-NAD; β-Nicotinamide Adenine Dinucleotide

UNSPSC

12352005

Hazard Statement

H303, H371

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/NAD_addition_.html

Purity

99.99

Solubility

H2O : 29.17 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O[C@@H]1[C@H](O)[C@@H](COP(OP(OC[C@@H](O[C@H]([C@@H]2O)N3C=NC4=C3N=CN=C4N)[C@H]2O)(O)=O)([O-])=O)O[C@H]1[N+]5=CC(C(N)=O)=CC=C5

Molecular Formula

C21H27N7O14P2

Molecular Weight

663.43

Precautions

H303, H371

References & Citations

[1]Viollet, B., et al., Cellular and molecular mechanisms of metformin: an overview. Clin Sci (Lond), 2012. 122 (6) : p. 253-70.|[2]Brandt, U., Energy converting NADH:quinone oxidoreductase (complex I) . Annu Rev Biochem, 2006. 75: p. 69-92.|[3]Kussmaul, L. and J. Hirst, The mechanism of superoxide production by NADH:ubiquinone oxidoreductase (complex I) from bovine heart mitochondria. Proc Natl Acad Sci U S A, 2006. 103 (20) : p. 7607-12.