Torsemide

Torsemide (Torasemide) is an orally active loop diuretic. Torsemide has anti-aldosterone and vasodilatory effects. Torsemide also can be used for the research of heart failure, renal disease and hepatic cirrhosis[1][1][3].

Product Specifications

CAS Number

[56211-40-6]

Product Name Alternative

Torasemide

UNSPSC

12352005

Hazard Statement

H319, H361

Target

NKCC

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Torsemide.html

Purity

99.83

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=S(C1=C(NC2=CC=CC(C)=C2)C=CN=C1)(NC(NC(C)C)=O)=O

Molecular Formula

C16H20N4O3S

Molecular Weight

348.42

Precautions

H319, H361

References & Citations

[1]Ishido, H., et al. Torasemide for the Treatment of Heart Failure. Cardiovascular & Hematological Disorders-Drug Targets. 2008. 8 (2), 127–132.|[2]Goodfriend, T. L., et al. Torsemide inhibits aldosterone secretion in vitro. Life Sciences. 1998. 63 (3), PL45–PL50.|[3]H A Friedel, et al. Torasemide. A review of its pharmacological properties and therapeutic potential. Drugs. 1991 Jan;41 (1) :81-103.