8-Hydroxy-2'-deoxyguanosine-13C,15N2
Product Specifications
UNSPSC Description
8-Hydroxy-2'-deoxyguanosine-13C,15N2 is 13C and 15N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis[1].
Target Antigen
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease;Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8-hydroxy-2-deoxyguanosine-13c-15n2.html
Smiles
O=C1C2=C(N=[13C]([15NH]1)[15NH2])N([C@H]3C[C@@H]([C@H](O3)CO)O)C(O)=N2
Molecular Weight
286.22
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.|[2]Valavanidis A, et al. 8-hydroxy-2' -deoxyguanosine (8-OHdG): A critical biomarker of oxidative stress and carcinogenesis. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2009 Apr;27(2):120-39.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W653916/8-Hydroxy-2-deoxyguanosine-13C-15N2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W653916/
Clinical Information
No Development Reported
Curated Selection
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