8-Hydroxy-2'-deoxyguanosine-13C,15N2

8-Hydroxy-2'-deoxyguanosine-13C,15N2 is 13C and 15N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis[1].

Product Specifications

Product Name Alternative

8-Oxo-2-Deoxyguanosine-13C,15N2

UNSPSC

12352005

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/8-hydroxy-2-deoxyguanosine-13c-15n2.html

Smiles

O=C1C2=C(N=[13C]([15NH]1)[15NH2])N([C@H]3C[C@@H]([C@H](O3)CO)O)C(O)=N2

Molecular Formula

C9 13CH13N3 15N2O5

Molecular Weight

286.22

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Valavanidis A, et al. 8-hydroxy-2' -deoxyguanosine (8-OHdG) : A critical biomarker of oxidative stress and carcinogenesis. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2009 Apr;27 (2) :120-39.