8-Hydroxy-2'-deoxyguanosine-13C,15N2
8-Hydroxy-2'-deoxyguanosine-13C,15N2 is 13C and 15N labeled 8-Hydroxy-2'-deoxyguanosine. 8-Hydroxy-2'-deoxyguanosine is a critical biomarker of oxidative stress and carcinogenesis[1].
Product Specifications
Product Name Alternative
8-Oxo-2-Deoxyguanosine-13C,15N2
UNSPSC
12352005
Target
Endogenous Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8-hydroxy-2-deoxyguanosine-13c-15n2.html
Smiles
O=C1C2=C(N=[13C]([15NH]1)[15NH2])N([C@H]3C[C@@H]([C@H](O3)CO)O)C(O)=N2
Molecular Formula
C9 13CH13N3 15N2O5
Molecular Weight
286.22
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Valavanidis A, et al. 8-hydroxy-2' -deoxyguanosine (8-OHdG) : A critical biomarker of oxidative stress and carcinogenesis. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2009 Apr;27 (2) :120-39.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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