1-Hydroxy-2-butanone
1-Hydroxy-2-butanone is a natural compound isolated from Bomboo Juice. 1-Hydroxy-2-butanone acts as a key intermediate for ethambutol. Ethambutol has anti-tuberculosis effects[1][2].
Product Specifications
CAS Number
[5077-67-8]
UNSPSC
12352211
Hazard Statement
H225, H315, H319, H335
Target
Bacterial; Drug Intermediate
Type
Natural Products
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/1-hydroxy-2-butanone.html
Purity
97.38
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
CCC(CO)=O
Molecular Formula
C4H8O2
Molecular Weight
88.11
Precautions
H225, H315, H319, H335
References & Citations
[1]Vanessa Faugeroux, et al. Synthesis and biological evaluation of conformationally constrained analogues of the antitubercular agent ethambutol. Bioorg Med Chem. 2007 Sep 1;15 (17) :5866-76.|[2]Lin H, et al. Efficient 1-hydroxy-2-butanone production from 1, 2-butanediol by whole cells of engineered E. coli. Catalysts, 2021, 11 (10) : 1184.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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