1-Hydroxy-2-butanone

1-Hydroxy-2-butanone is a natural compound isolated from Bomboo Juice. 1-Hydroxy-2-butanone acts as a key intermediate for ethambutol. Ethambutol has anti-tuberculosis effects[1][2].

Product Specifications

CAS Number

[5077-67-8]

UNSPSC

12352211

Hazard Statement

H225, H315, H319, H335

Target

Bacterial; Drug Intermediate

Type

Natural Products

Related Pathways

Anti-infection; Others

Applications

COVID-19-immunoregulation

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/1-hydroxy-2-butanone.html

Purity

97.38

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

CCC(CO)=O

Molecular Formula

C4H8O2

Molecular Weight

88.11

Precautions

H225, H315, H319, H335

References & Citations

[1]Vanessa Faugeroux, et al. Synthesis and biological evaluation of conformationally constrained analogues of the antitubercular agent ethambutol. Bioorg Med Chem. 2007 Sep 1;15 (17) :5866-76.|[2]Lin H, et al. Efficient 1-hydroxy-2-butanone production from 1, 2-butanediol by whole cells of engineered E. coli. Catalysts, 2021, 11 (10) : 1184.