SARS-CoV-2 3CLpro-IN-15

SARS-CoV-2 3CLpro-IN-15 (compound a) is a beta-nitrostyrene coronavirus SARS-CoV-2 inhibitor that targets the SARS-CoV-2 3CL protease (3CLpro) . SARS-CoV-2 3CLpro-IN-15 inhibits viral replication and transcription and plays a key role in the discovery of anti-COVID-19 lead compounds[1].

Product Specifications

CAS Number

[3156-41-0]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

SARS-CoV; Virus Protease

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sars-cov-2-3clpro-in-15.html

Solubility

10 mM in DMSO

Smiles

[O-][N+](/C=C/C1=CC=C([N+]([O-])=O)C=C1)=O

Molecular Formula

C8H6N2O4

Molecular Weight

194.14

Precautions

P261-P280-P302+P352

References & Citations

[1]Jia ZJ, et al. Synthesis, molecular docking, and binding Gibbs free energy calculation of β-nitrostyrene derivatives: Potential inhibitors of SARS-CoV-2 3CL protease. J Mol Struct. 2023 Jul 15;1284:135409..