Dehydrodanshenol A

Dehydrodanshenol A is a non-competitive inhibitor of Protein tyrosine phosphatase 1B (PTP1B), with an IC50 value of 8.5 μM. Dehydrodanshenol A can be used in diabetes-related research[1].

Product Specifications

CAS Number

[1444618-61-4]

UNSPSC

12352005

Target

Phosphatase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/dehydrodanshenol-a.html

Solubility

10 mM in DMSO

Smiles

CC(C[C@@]1(C2=C(C=CC=C3C)C3=CC=C2C4=C(C(C)=CO4)C1=O)O)=O

Molecular Formula

C21H18O4

Molecular Weight

334.37

References & Citations

[1]Kim DH, et al. Characterization of the inhibitory activity of natural tanshinones from Salvia miltiorrhiza roots on protein tyrosine phosphatase 1B. Chem Biol Interact. 2017 Dec 25;278:65-73.