Human CD8 alpha Recombinant Mouse Monoclonal Antibody [PSH04-94]
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen-presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Two alternative transcripts encoding distinct isoforms, one membrane associated and one secreted, have been identified.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
CD8A
Swiss Prot
P01732 Human
Cellular Locus
Cell membrane; Secreted.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within
Isotype
IgG1
Clone
PSH04-94
Conjugation
Non-conjugated
Type
Recombinant Mouse monoclonal Antibody
Applications
FC
Positive Control
Human peripheral blood lymphocytes.
Concentration
1 mg/mL
Dilution
FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4).
Molecular Weight
Predicted band size: 26 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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