Alizapride-13C,d3 (hydrochloride)
Product Specifications
UNSPSC Description
Alizapride-13C,d3 (hydrochloride) is deuterium labeled Alizapride (hydrochloride). Alizapride hydrochloride is a dopamine receptor antagonist with prokinetic and antiemetic effects which can also be used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.
Target Antigen
Dopamine Receptor; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein;Neuronal Signaling;Others
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC2=C(C=C1O[13C]([2H])([2H])[2H])NN=N2)NCC3N(CCC3)CC=C.Cl
Molecular Weight
355.84
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.|[2]Bleiberg H, et al. Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial. Cancer Chemother Pharmacol. 1988;22(4):316-20.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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