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Alizapride-13C, d3 (hydrochloride)

Alizapride-13C, d3 (hydrochloride) is deuterium labeled Alizapride (hydrochloride) . Alizapride hydrochloride is a dopamine receptor antagonist with prokinetic and antiemetic effects which can also be used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.

Product Specifications

UNSPSC

12352005

Target

Dopamine Receptor; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC2=C(C=C1O[13C]([2H])([2H])[2H])NN=N2)NCC3N(CCC3)CC=C.Cl

Molecular Formula

C15 13CH19D3ClN5O2

Molecular Weight

355.84

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Bleiberg H, et al. Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial. Cancer Chemother Pharmacol. 1988;22 (4) :316-20.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Isoform

D3 Receptor

Available Sizes

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