10-Deacetyl-13-oxobaccatin III
Product Specifications
UNSPSC Description
10-Deacetyl-13-oxobaccatin III is an taxane that can be isolated from Taxus sumatrana. 10-Deacetyl-13-oxobaccatin III (30 μg/mL) shows cytotoxicity against A498, NCI-H226, A549, PC-3 cells, with inhibition a rate of 29.7%, 49.2%, 43.9%, 65.3%[1].
Target Antigen
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/10-deacetyl-13-oxobaccatin-iii.html
Solubility
10 mM in DMSO
Smiles
O=C([C@]1(C)[C@@H](O)C[C@@H]2[C@](CO2)(OC(C)=O)[C@@]1([H])[C@H](OC(C3=CC=CC=C3)=O)[C@](C4(C)C)(O)C5)[C@H](O)C4=C(C)C5=O
Molecular Weight
542.57
References & Citations
[1]Shen YC, et al. Three new taxane diterpenoids from Taxus sumatrana. J Nat Prod. 2005 Jan;68(1):90-3.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W778562/10-Deacetyl-13-oxobaccatin-III-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W778562/
Clinical Information
No Development Reported
CAS Number
92950-42-0
Available Sizes
Curated Selection
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