N-Nitrosodiethylamine-d10
N-Nitrosodiethylamine-d10 is the deuterium labeled N-Nitrosodiethylamine[1]. N-Nitrosodiethylamine (Diethylnitrosamine) is a potent hepatocarcinogenic dialkylnitrosoamine. N-Nitrosodiethylamine is mainly present in tobacco smoke, water, cheddar cheese, cured, fried meals and many alcoholic beverages. N-Nitrosodiethylamine is responsible for the changes in the nuclear enzymes associated with DNA repair/replication. N-Nitrosodiethylamine results in various tumors in all animal species. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.
Product Specifications
CAS Number
[1219794-54-3]
Product Name Alternative
Diethylnitrosamine-d10; DEN-d10; DENA-d10
UNSPSC
12352211
Hazard Statement
H301-H341-H350-H412
Target
DNA/RNA Synthesis
Type
Isotope-Labeled Compounds
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
99.90
Solubility
H2O : ≥ 100 mg/mL
Smiles
[2H]C([2H])([2H])C([2H])([2H])N(N=O)C([2H])([2H])C([2H])([2H])[2H]
Molecular Formula
C4D10N2O
Molecular Weight
112.20
Precautions
P264-P280-P501
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
Colloidal Gold Conjugated Goat Affinity Purified Antibody to Mouse IgM, 30nm
DDX55 (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 55, FLJ16577, KIAA1595, MGC33209)