High HAMA Serum and Plasma Matched Set

<strong>High HAMA Serum and Plasma Matched Set</strong>_x000D_ <table width="643">_x000D_ <tbody>_x000D_ <tr>_x000D_ <td>Catalog number:</td>_x000D_ <td>S2010006P</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Lot number:</td>_x000D_ <td>Batch Dependent</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Expiration date:</td>_x000D_ <td>Batch Dependent</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Volume:</td>_x000D_ <td>2 x 1 mL (1 mL serum and 1 mL K3 EDTA Plasma)</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Appearance:</td>_x000D_ <td>Yellow orange</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Matrix:</td>_x000D_ <td>Human serum and plasma</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Storage:</td>_x000D_ <td>At -20°C or lower. Avoid repeated freeze-thaw cycles. Aliquot as needed.</td>_x000D_ </tr>_x000D_ <tr>_x000D_ <td>Keywords</td>_x000D_ <td>HAMA sample, Human Anti-Mouse Antibodies serum, High HAMA plasma</td>_x000D_ </tr>_x000D_ </tbody>_x000D_ </table>_x000D_ &nbsp;_x000D_ _x000D_ <strong>About HAMA</strong>_x000D_ _x000D_ Immunoassays rely heavily on mouse antibodies for the detection of various analytes. The accuracy of these assays can, however, suffer when samples contain human anti-mouse antibodies (HAMA). Indeed, HAMA are often associated with inaccurate results because they can bind to both capture and detection antibodies and can generate non-specific signals. This so-called HAMA effect is major interference issue. Assessing the tolerance of an immunoassay to HAMA and mitigating it is very important important during research and development._x000D_ _x000D_ <strong>Products Related to High HAMA Serum and Plasma Matched Set: <a href="https://moleculardepot.com/product/high-hama-serum/">High HAMA Serum</a></strong>_x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Mukherjee S, Ayanambakkam A, Ibrahimi S, Schmidt S, Charkrabarty JH, Khawandanah M. Ibritumomab tiuxetan (Zevalin) and elevated serum human anti-murine antibody (HAMA) Hematol Oncol Stem Cell Ther. 2018 Sep;11(3):187-188._x000D_ 2: Klee GG. Human anti-mouse antibodies Arch Pathol Lab Med. 2000 Jun;124(6):921-3._x000D_ 3: Wang G, An Y, Zhang X, Ding P, Bi H, Zhao Z. Chondrocyte Spheroids Laden in GelMA/HAMA Hybrid Hydrogel for Tissue-Engineered Cartilage with Enhanced Proliferation, Better Phenotype Maintenance, and Natural Morphological Structure Gels. 2021 Dec 2;7(4):247._x000D_ 4: Mouser VH, Abbadessa A, Levato R, Hennink WE, Vermonden T, Gawlitta D, Malda J. Development of a thermosensitive HAMA-containing bio-ink for the fabrication of composite cartilage repair constructs Biofabrication. 2017 Mar 23;9(1):015026._x000D_ 5: Maier W, Buller R, Philipp M, Heuser I. The Hamilton Anxiety Scale: reliability, validity and sensitivity to change in anxiety and depressive disorders J Affect Disord. 1988 Jan-Feb;14(1):61-8._x000D_ 6: Imasaka KI, Tomita Y. Reply Ann Thorac Surg. 2018 Oct;106(4):1264-1265._x000D_ 7: Imasaka KI, Tomita Y. Reply Ann Thorac Surg. 2018 Oct;106(4):1258-1259._x000D_ 8: Xia C, Chen P, Mei S, Ning L, Lei C, Wang J, Zhang J, Ma J, Fan S. Photo-crosslinked HAMA hydrogel with cordycepin encapsulated chitosan microspheres for osteoarthritis treatment Oncotarget. 2017 Jan 10;8(2):2835-2849._x000D_ 9: Kasper S, Gastpar M, Müller WE, Volz HP, Möller HJ, Schläfke S, Dienel A. Lavender oil preparation Silexan is effective in generalized anxiety disorder--a randomized, double-blind comparison to placebo and paroxetine Int J Neuropsychopharmacol. 2014 Jun;17(6):859-69._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/20718076">10: Matza LS, Morlock R, Sexton C, Malley K, Feltner D. Identifying HAM-A cutoffs for mild, moderate, and severe generalized anxiety disorder Int J Methods Psychiatr Res. 2010 Dec;19(4):223-32. </a>