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4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione

4,10-Dioxatri cyclo[5.2. 1.02.6]dec-8-ene-3,5-dione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

[5426-09-5]

Product Name Alternative

7-Oxanorborna-2-ene-5,6-dicarboxylic anhydride

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/4-10-dioxatri-cyclo-5-2-1-02-6-dec-8-ene-3-5-dione.html

Purity

97.0

Solubility

DMSO : ≥ 100 mg/mL

Smiles

C1=CC2C3C(C1O2)C(=O)OC3=O

Molecular Formula

C8H6O4

Molecular Weight

166.13

Precautions

H315, H319, H335

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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