[Au (TPP) ]Cl

[Au (TPP) ]Cl inhibits the refolding activity of the Hsp60-Hsp10 complex with significant anticancer activities[1][2].

Product Specifications

CAS Number

[15695-27-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

HSP

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/au-tpp-cl.html

Purity

95.00

Smiles

[N-]12[Au+3]34[N-]5C6=CC=C5C(C7=CC=CC=C7)=C(C=C8)[N]3=C8C(C9=CC=CC=C9)=C1C=CC2=C(C%10=CC=CC=C%10)C%11=[N]4C(C=C%11)=C6C%12=CC=CC=C%12.[Cl-]

Molecular Formula

C44H28AuClN4

Molecular Weight

845.14

Precautions

H302, H315, H319, H335

References & Citations

[1]Qianli Meng, et al. Toward Developing Chemical Modulators of Hsp60 as Potential Therapeutics. Front Mol Biosci. 2018 Apr 20:5:35.|[2]Di Hu, et al. Anticancer Gold (III) Porphyrins Target Mitochondrial Chaperone Hsp60. Angew Chem Int Ed Engl. 2016 Jan 22;55 (4) :1387-91.