Dihydrolanosterol-d7

Dihydrolanosterol-d7 is deuterium labeled Dihydrolanosterol. Dihydrolanosterol is a subtrate of CYP51 and a cholesterol biosynthesis inhibitor[1].

Product Specifications

CAS Number

[2260669-12-1]

UNSPSC

12352211

Target

Cytochrome P450; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Purity

99.0

Solubility

10 mM in DMSO

Smiles

C[C@]12C3=C(CC[C@@]1([C@@](CC2)([H])[C@H](C)CCCC(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])C)[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC3)C

Molecular Formula

C30H45D7O

Molecular Weight

435.78

References & Citations

[1]Lepesheva GI, Waterman MR. Sterol 14alpha-demethylase cytochrome P450 (CYP51), a P450 in all biological kingdoms. Biochim Biophys Acta. 2007;1770 (3) :467-477.|[2]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-223.