SB297006
SB297006 is a CCR3 antagonist, which significantly inhibits proliferation and neurosphere formation in CCL11-treated neural progenitor cells.
Product Specifications
CAS Number
58816-69-6
UNSPSC
12352005
Hazard Statement
H302, H372, H400
Target
CCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/SB297006.html
Purity
99.86
Solubility
DMSO : 150 mg/mL (ultrasonic)
Smiles
O=C(OCC)[C@H](CC1=CC=C([N+]([O-])=O)C=C1)NC(C2=CC=CC=C2)=O
Molecular Formula
C18H18N2O5
Molecular Weight
342.35
Precautions
H302, H372, H400
References & Citations
[1]Wang F, et al. CCL11 promotes migration and proliferation of mouse neural progenitor cells. Stem Cell Res Ther. 2017 Feb 7;8 (1) :26.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CCR3
Available Sizes
Frequently Asked Questions
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