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SB297006

SB297006 is a CCR3 antagonist, which significantly inhibits proliferation and neurosphere formation in CCL11-treated neural progenitor cells.

Product Specifications

CAS Number

[58816-69-6]

UNSPSC

12352005

Hazard Statement

H302, H372, H400

Target

CCR

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/SB297006.html

Purity

99.86

Solubility

DMSO : 150 mg/mL (ultrasonic)

Smiles

O=C(OCC)[C@H](CC1=CC=C([N+]([O-])=O)C=C1)NC(C2=CC=CC=C2)=O

Molecular Formula

C18H18N2O5

Molecular Weight

342.35

Precautions

H302, H372, H400

References & Citations

[1]Wang F, et al. CCL11 promotes migration and proliferation of mouse neural progenitor cells. Stem Cell Res Ther. 2017 Feb 7;8 (1) :26.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CCR3

Available Sizes

Curated Selection

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