GAC0001E5
GAC0001E5 is an LXR inverse agonist. GAC0001E5 has antiproliferative activity and can be used in cancer research[1].
Product Specifications
CAS Number
[927969-67-3]
UNSPSC
12352005
Target
LXR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gac0001e5.html
Purity
98.57
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1N=C(NC(C2=CC=CC=C2)=C1)NC3=CC=CC(C(F)(F)F)=C3
Molecular Formula
C17H12F3N3O
Molecular Weight
331.29
References & Citations
[1]Karaboga H, et al. Screening of Focused Compound Library Targeting Liver X Receptors in Pancreatic Cancer Identified Ligands with Inverse Agonist and Degrader Activity. ACS Chem Biol. 2020 Nov 20;15 (11) :2916-2928.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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