BTS 39542

BTS 39542 is an orally active inhibitor for Na+ K+ Cl cotransport system, that exhibits diuretic activity, and can be used in hypertension and edema research[1].

Product Specifications

CAS Number

[57410-31-8]

UNSPSC

12352005

Target

Chloride Channel; Potassium Channel; Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/bts-39542.html

Smiles

O=C(CC1N(NC(C2=C1C=C(C=C2)Cl)=O)C3=CC=C4SN=NC4=C3)O

Molecular Formula

C16H11ClN4O3S

Molecular Weight

374.80

References & Citations

[1]Aiton JF, et al., Diuretic action of BTS 39542 (dihydrophthalazin-1-ylacetic acid) is consistent with inhibition of Na + K + Cl cotransport. Biochem Pharmacol. 1982 Sep 1;31 (17) :2827-30.