ADAMTS7-IN-1
ADAMTS7-IN-1 (Compound 3a) is an effective and selective inhibitor of ADAMTS7 with a Ki value of 9 nM. ADAMTS7-IN-1 can be used in the research of atherosclerosis[1].
Product Specifications
UNSPSC
12352005
Target
ADAMTS
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/adamts7-in-1.html
Purity
98.91
Solubility
DMSO : 200 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(N1CCC([C@H](C(NO)=O)NS(C2=CC=C(C3=CC=C(C(F)(F)F)C=C3)C=C2)(=O)=O)CC1)C4=CC=CC=C4
Molecular Formula
C27H26F3N3O5S
Molecular Weight
561.57
References & Citations
[1]Cuffaro D, et al. Design, synthesis and biological evaluation of arylsulfonamides as ADAMTS7 inhibitors[J]. RSC Medicinal Chemistry, 2024.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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