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ADAMTS7-IN-1

ADAMTS7-IN-1 (Compound 3a) is an effective and selective inhibitor of ADAMTS7 with a Ki value of 9 nM. ADAMTS7-IN-1 can be used in the research of atherosclerosis[1].

Product Specifications

UNSPSC

12352005

Target

ADAMTS

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/adamts7-in-1.html

Purity

98.91

Solubility

DMSO : 200 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(N1CCC([C@H](C(NO)=O)NS(C2=CC=C(C3=CC=C(C(F)(F)F)C=C3)C=C2)(=O)=O)CC1)C4=CC=CC=C4

Molecular Formula

C27H26F3N3O5S

Molecular Weight

561.57

References & Citations

[1]Cuffaro D, et al. Design, synthesis and biological evaluation of arylsulfonamides as ADAMTS7 inhibitors[J]. RSC Medicinal Chemistry, 2024.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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