HT-2 Toxin-13C22

HT-2 Toxin-13C22 is 13C-labeled HT-2 Toxin (HY-N6729). HT-2 Toxin is an active, deacetylated metabolite of the T-2 toxin. HT-2 toxin inhibits protein synthesis and cell proliferation in plants[1][2][3].

[13CH3][13C@@]12[13C@@]3([13C@]([H])(O[13C@]4([13C@]2([13CH2]O[13C]([13CH3])=O)[13CH2][13C@H](O[13C]([13CH2][13CH]([13CH3])[13CH3])=O)[13C]([13CH3])=[13CH]4)[H])[13C@H](O)[13C@H]1O)[13CH2]O3

[1]Berthiller, F., et al. Masked mycotoxins: A review Mol.Nutr.Food Res. 57, 165-186 (2013).|[2]Nathanail, A.V., et al. Metabolism of the fusarium mycotoxins T-2 toxin and HT-2 toxin in wheat J.Agric.Food Chem 63(35), 7862-7872 (2015).|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-220.