SIRP gamma, Cynomolgus (HEK293, His)

SIRP gamma Protein, a member of signal-regulatory protein (SIRP) family, is the only SIRP detected on T cells and activated NK cells. SIRP gamma can bind CD47, providing T cells and NK cells with a cell surface molecule capable of interacting with CD47. SIRP gamma-CD47 interaction mediates strong cell-cell adhesion and supports T cell-APC contact, enhancing antigen presentation and consequent T-cell proliferation and cytokine secretion. SIRP gamma Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived SIRP gamma protein, expressed by HEK293 , with C-His labeled tag.

EEELQMIQPE KLLLVAVGES ATLNCTVTSL LPVGPVLWFR GVGPGRELIY NQKEGHFPRV TTVSDLTKRN NMDFSIRISS ITPADAGTYY CVKFRKGSPE NVEFKSGPGT EMALRAKPSA PVVSGPAARA TPEHTVSFTC KSHGFSPRDI TLKWFKNGNE LSDFQTNVDP AGQSVSYSIR STARVVLAPW DVRSQVTCEV AHVTLQGDPL RGTANLSEAI RVPPTLEVTQ QPIRAGNQVN ITYQVRNFYP QNLQLTWLEN GNVCRTETAS TLTENKDGTY NWTSWLLVNT SDQRDDVVLT CQVKHDGQLA VNKSLVLEVS AHQKDQSSDA TH