(Rac) -Anemonin

(Rac) -Anemonin ((Rac) -Pulsatilla camphor) is the diastereoisomer of Anemonin (HY-N0278) . Anemonin (Pulsatilla camphor), a selective iNOS inhibitor, is also a PKC-θ inhibitor. Anemonin can significantly inhibit the translation or protein stability of PKC-θ protein. Anemonin also ameliorates dextran sodium sulfate-induced acute ulcerative colitis (UC) in mice. Anemonin can be used in the research of inflammation-related diseases[1][2].

Product Specifications

CAS Number

[90921-11-2]

Product Name Alternative

(Rac) -Pulsatilla camphor; (Rac) -Anemonine

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

NO Synthase; PKC

Type

Natural Products

Related Pathways

Epigenetics; Immunology/Inflammation; TGF-beta/Smad

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/rac-anemonin.html

Purity

98.19

Solubility

10 mM in DMSO

Smiles

O=C1C=CC2(C3(CC2)C=CC(O3)=O)O1

Molecular Formula

C10H8O4

Molecular Weight

192.17

Precautions

H302, H315, H319, H335

References & Citations

[1]Jiang L, et al. Anti-inflammatory effects of anemonin on acute ulcerative colitis via targeted regulation of protein kinase C-θ. Chin Med. 2022 Mar 28;17 (1) :39.|[2]Lee TH, et al. Anemonin, from Clematis crassifolia, potent and selective inducible nitric oxide synthase inhibitor. J Ethnopharmacol. 2008 Mar 28;116 (3) :518-27.