DAPD-NHc-pr
DAPD-NHc-pr (compound 12) is an HIV inhibitor with EC50/EC90 values of 0.85 μM and 13 μM, respectively. DAPD-NHc-pr shows no toxicity to normal cells (PBM, CEM, VERO) [1].
Product Specifications
CAS Number
280138-71-8
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/dapd-nhc-pr.html
Smiles
NC1=NC(NC2CC2)=C3N=CN([C@@H]4O[C@H](CO)OC4)C3=N1
Molecular Formula
C12H16N6O3
Molecular Weight
292.29
References & Citations
[1]Narayanasamy J, et al. Synthesis and anti-HIV activity of (-) -beta-D- (2R,4R) -1,3-dioxolane-2,6-diamino purine (DAPD) (amdoxovir) and (-) -beta-D- (2R,4R) -1,3-dioxolane guanosine (DXG) prodrugs. Antiviral Res. 2007 Sep;75 (3) :198-209.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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