PT-91
PT-91 is an agonist of GPR27. PT-91 exhibits high metabolic stability and brain exposure in mice[1].
Product Specifications
CAS Number
[3037561-48-8]
UNSPSC
12352005
Target
Orphan GPCR; Orphan Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pt-91.html
Concentration
10mM
Purity
98.25
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1=CC=C(C=C1OC)C(F)(F)F)NC2=CC=C(C=C2)S(NC3=CC=CC=C3)(=O)=O
Molecular Formula
C21H17F3N2O4S
Molecular Weight
450.43
References & Citations
[1]Pillaiyar T, et al. Development of Ligands for the Super Conserved Orphan G Protein-Coupled Receptor GPR27 with Improved Efficacy and Potency. J Med Chem. 2023 Dec 7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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