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PT-91

PT-91 is an agonist of GPR27. PT-91 exhibits high metabolic stability and brain exposure in mice[1].

Product Specifications

CAS Number

[3037561-48-8]

UNSPSC

12352005

Target

Orphan GPCR; Orphan Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/pt-91.html

Concentration

10mM

Purity

98.25

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(C1=CC=C(C=C1OC)C(F)(F)F)NC2=CC=C(C=C2)S(NC3=CC=CC=C3)(=O)=O

Molecular Formula

C21H17F3N2O4S

Molecular Weight

450.43

References & Citations

[1]Pillaiyar T, et al. Development of Ligands for the Super Conserved Orphan G Protein-Coupled Receptor GPR27 with Improved Efficacy and Potency. J Med Chem. 2023 Dec 7.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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