93-O17S
93-O17S is an ionizable lipid. 93-O17S is involved in the construction of LNP. 93-O17S can achieve mRNA delivery to the spleen[1][2].
Product Specifications
CAS Number
2227008-67-3
UNSPSC
12352005
Hazard Statement
H225, H319
Target
Liposome
Type
Oligonucleotides
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/93-o17s.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : ≥ 100 mg/mL
Smiles
O=C(CCN(CCCN1C=NC=C1)CCC(OCCSCCCCCCCCCCCCCC)=O)OCCSCCCCCCCCCCCCCC
Molecular Formula
C44H83N3O4S2
Molecular Weight
782.28
Precautions
H225, H319
References & Citations
[1]Omo-Lamai S, et al. Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape Without Side Effects. bioRxiv [Preprint]. 2024 Apr 18:2024.04.16.589801.|[2]Delehedde C, et al. Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles. Pharmaceutics. 2021 Jun 24;13 (7) :945.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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