Cathepsin D Substrate I

<strong>Cathepsin D Substrate I</strong>_x000D_ <strong>Catalog number:</strong> B2013462_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 5 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 882 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> Cathepsin D Substrate I, Bz-RGFFP-4-MeOβNA, HCl_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Minarowska A, Gacko M, Karwowska A, Minarowski Ł. Human cathepsin D Folia Histochem Cytobiol. 2008;46(1):23-38._x000D_ 2: Gacko M, Minarowska A, Karwowska A, Minarowski Ł. Cathepsin D inhibitors Folia Histochem Cytobiol. 2007;45(4):291-313._x000D_ 3: Zhang Z, Nakata E, Shibano Y, Morii T. FRET-Based Cathepsin Probes for Simultaneous Detection of Cathepsin B and D Activities Chembiochem. 2022 Oct 6;23(19):e202200319._x000D_ 4: Vidoni C, Follo C, Savino M, Melone MA, Isidoro C. The Role of Cathepsin_D in the Pathogenesis of Human Neurodegenerative Disorders Med Res Rev. 2016 Sep;36(5):845-70._x000D_ 5: Pedram K, Laqtom NN, Shon DJ, Di Spiezio A, Riley NM, Saftig P, Abu-Remaileh M, Bertozzi CR. Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals Proc Natl Acad Sci U S A. 2022 Sep 27;119(39):e2117105119._x000D_ 6: Azaryan AV, Galoyan AA. Substrate specificity of cerebral cathepsin D and high-Mr aspartic endopeptidase J Neurosci Res. 1988 Feb;19(2):268-71._x000D_ 7: Agarwal NS, Rich DH. Inhibition of cathepsin D by substrate_analogues containing statine and by analogues of pepstatin J Med Chem. 1986 Dec;29(12):2519-24._x000D_ 8: Liaudet-Coopman E, Beaujouin M, Derocq D, Garcia M, Glondu-Lassis M, Laurent-Matha V, Prébois C, Rochefort H, Vignon F. Cathepsin D: newly discovered functions of a long-standing aspartic protease in cancer and apoptosis Cancer Lett. 2006 Jun 18;237(2):167-79._x000D_ 9: Agarwal N, Rich DH. An improved cathepsin-D substrate and assay procedure Anal Biochem. 1983 Apr 1;130(1):158-65._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/29367161">10: Cornelio VE, de Moraes MC, Domingues VC, Fernandes JB, da Silva MFDGF, Cass QB, Vieira PC. Cathepsin D immobilized capillary reactors for on-flow screening assays J Pharm Biomed Anal. 2018 Mar 20;151:252-259. </a>_x000D_ _x000D_ <strong>Products Related to Cathepsin D Substrate I can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>