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Parogrelil (hydrochloride)

Parogrelil (hydrochloride) (NM-702) is a phosphodiesterase inhibitor with activity in inhibiting intermittent claudication. Parogrelil (hydrochloride) selectively inhibits PDE3, inhibits human platelet aggregation in vitro and rat aortic contraction, and improves walking distance and plantar surface temperature in the rat femoral artery ligation model, with better effects than cilostazol.

Product Specifications

CAS Number

139145-84-9

Product Name Alternative

NM-702; NT-702

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/parogrelil-hydrochloride.html

Smiles

O=C1C(Br)=C(NCC2=CC=CN=C2)C(OCCCC3=CC=C(Cl)C=C3)=NN1.Cl

Molecular Formula

C19H19BrCl2N4O2

Molecular Weight

486.19

References & Citations

[1]NT-702 (parogrelil hydrochloride, NM-702), a novel and potent phosphodiesterase inhibitor, improves reduced walking distance and lowered hindlimb plantar surface temperature in a rat experimental intermittent claudication model

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 3

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