AChE-IN-57
AChE-IN-57 (compound 5b (SP-2) ) is a potent AChE inhibitor. AChE-IN-57 improves cognitive defects. AChE-IN-57 restores the biochemical mediators and inhibits reactive oxygen and nitrogen species implicated in the neuroinflammation mechanism. AChE-IN-57 has the potential for the research of Alzheimer[1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-in-57.html
Solubility
10 mM in DMSO
Smiles
ClC(C=C1)=CC=C1NC2=NC(NCCN3CCCCC3)=NC=C2
Molecular Formula
C17H22ClN5
Molecular Weight
331.84
References & Citations
[1]Pant S, et al. Novel Substituted Pyrimidine Derivatives as Potential Anti-Alzheimer's Agents: Synthesis, Biological, and Molecular Docking Studies. ACS Chem Neurosci. 2024 Feb 21;15 (4) :783-797.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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