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AChE-IN-57

AChE-IN-57 (compound 5b (SP-2) ) is a potent AChE inhibitor. AChE-IN-57 improves cognitive defects. AChE-IN-57 restores the biochemical mediators and inhibits reactive oxygen and nitrogen species implicated in the neuroinflammation mechanism. AChE-IN-57 has the potential for the research of Alzheimer[1].

Product Specifications

UNSPSC

12352005

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ache-in-57.html

Solubility

10 mM in DMSO

Smiles

ClC(C=C1)=CC=C1NC2=NC(NCCN3CCCCC3)=NC=C2

Molecular Formula

C17H22ClN5

Molecular Weight

331.84

References & Citations

[1]Pant S, et al. Novel Substituted Pyrimidine Derivatives as Potential Anti-Alzheimer's Agents: Synthesis, Biological, and Molecular Docking Studies. ACS Chem Neurosci. 2024 Feb 21;15 (4) :783-797.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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