12:0 Coenzyme A (triammonium)

12:0 Coenzyme A (Lauroyl coenzyme A triammonium) is an intermediary in fatty acid synthesis or metabolism, formed by combining long-chain fatty acids (or lauric acid) with coenzyme A. 12:0 Coenzyme A is involved in lipid biosynthesis and fatty acid transport, in which coenzyme A acts as a transport molecule to help move and target specific compounds[1][2].

Product Specifications

CAS Number

[799812-84-3]

Product Name Alternative

Lauroyl coenzyme A (triammonium) ; S-Dodecanoate-CoA (triammonium) ; S-Dodecanoate-CoA (triammonium)

UNSPSC

12352204

Target

Biochemical Assay Reagents; Endogenous Metabolite

Type

Enzyme

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/12-0-coenzyme-a.html

Solubility

10 mM in DMSO

Smiles

O[C@@H]1[C@H](OP(O)(O)=O)[C@@H](COP(OP(OCC(C)(C)[C@@H](O)C(NCCC(NCCSC(CCCCCCCCCCC)=O)=O)=O)(O)=O)(O)=O)O[C@H]1N2C=NC3=C(N)N=CN=C32.N.N.N

Molecular Formula

C33H67N10O17P3S

Molecular Weight

1000.93

References & Citations

[1]Musayev F, et al. Crystal structure of a substrate complex of Mycobacterium tuberculosis β-ketoacyl-acyl carrier protein synthase III (FabH) with lauroyl-coenzyme A[J]. Journal of molecular biology, 2005, 346 (5) : 1313-1321.|[2]Oba Y, Sato M, Ojika M, et al. Enzymatic and genetic characterization of firefly luciferase and Drosophila CG6178 as a fatty acyl-CoA synthetase[J]. Bioscience, biotechnology, and biochemistry, 2005, 69 (4) : 819-828.