Pomalidomide-CO-C3-PEG4-C6-NH2
Pomalidomide-CO-C3-PEG4-C6-NH2 is an E3 ligase ligand-linker conjugate part of PROTAC PIPIB degrader 1. Pomalidomide consists of the E3 ligase ligand Pomalidomide (HY-10984) and a linker[1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-co-c3-peg4-c6-nh2.html
Smiles
NCCCCCCOCCOCCOCCOCCCCCC(NC1=C2C(C(N(C3C(NC(CC3)=O)=O)C2=O)=O)=CC=C1)=O
Molecular Formula
C31H46N4O9
Molecular Weight
618.72
References & Citations
[1]Yang Z, et al. Discovery of Selective Proteolysis-Targeting Chimera Degraders Targeting PTP1B as Long-Term Hypoglycemic Agents. J Med Chem. 2024 May 9;67 (9) :7569-7584.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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