Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Diethyl succinate (Standard)

Diethyl succinate (Standard) is the analytical standard of Diethyl succinate. This product is intended for research and analytical applications. Diethyl succinate (Diethyl Butanedioate) can be utilized at physiological pH, allowing it to penetrate biological membranes and integrate into the cells of tissue cultures, where it is metabolized via the tricarboxylic acid cycle. Diethyl succinate modulates the polarization and activation of microglial cells by reducing mitochondrial fission and the levels of reactive oxygen species (ROS), thereby exerting an inflammatory protective effect in primary microglial cells. Furthermore, Diethyl succinate is non-toxic and can be used in flavorings and seasonings[1][2].

Product Specifications

CAS Number

123-25-1

Product Name Alternative

Diethyl Butanedioate (Standard)

UNSPSC

12352211

Target

Biochemical Assay Reagents; Reactive Oxygen Species (ROS) ; Reference Standards

Type

Reference Standards

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/diethyl-succinate-standard.html

Smiles

O=C(OCC)CCC(OCC)=O

Molecular Formula

C8H14O4

Molecular Weight

174.19

References & Citations

[1]Zacharias NM, et al. Real-time molecular imaging of tricarboxylic acid cycle metabolism in vivo by hyperpolarized 1- (13) C diethyl succinate. J Am Chem Soc. 2012 Jan 18;134 (2) :934-43.|[2]Lixiang Wang, et al. "Diethyl succinate modulates microglial polarization and activation by reducing mitochondrial fission and cellular ROS." Metabolites 11.12 (2021) : 854.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Necitumumab Biosimilar - Research Grade
ICH5121-10mg 10 mg (2x 5 mg)

Necitumumab Biosimilar - Research Grade

Sign In for Pricing
View Details
PROCR Rabbit Polyclonal Antibody
AP17203PU-N 400 µL

PROCR Rabbit Polyclonal Antibody

Sign In for Pricing
View Details
Heptaminol Hydrochloride
TRC-H546160-250MG 250 mg

Heptaminol Hydrochloride

Sign In for Pricing
View Details
Beta Amyloid 1-40 Recombinant Rabbit monoclonal Antibody
HA750789 100 µL

Beta Amyloid 1-40 Recombinant Rabbit monoclonal Antibody

Sign In for Pricing
View Details
trans,trans-Muconic Acid-d4
TRC-M791000-5MG 5 mg

trans,trans-Muconic Acid-d4

Sign In for Pricing
View Details
6-Azidohexan-1-amine (~90%)
TRC-A965850-10MG 10 mg

6-Azidohexan-1-amine (~90%)

Sign In for Pricing
View Details