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Safingol (hydrochloride)

Safingol hydrochloride is a lyso-sphingolipid PKC (protein kinase C) inhibitor[1].

Product Specifications

CAS Number

139755-79-6

Product Name Alternative

L-threo-dihydrosphingosine (hydrochloride)

UNSPSC

12352211

Target

PKC

Type

Reference compound

Related Pathways

Epigenetics; TGF-beta/Smad

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/safingol-hydrochloride.html

Smiles

CCCCCCCCCCCCCCC[C@H](O)[C@@H](N)CO.Cl

Molecular Formula

C18H40ClNO2

Molecular Weight

337.97

References & Citations

[1]Tsukamoto S, et al. Sphingosine Kinase-1 Protects Multiple Myeloma from Apoptosis Driven by Cancer-Specific Inhibition of RTKs. Mol Cancer Ther. 2015 Oct;14 (10) :2303-12.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Frequently Asked Questions

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