2-Hydroxyemodin
2-Hydroxyemodin is an active metabolite of emodin in the hepatic microsomes. Emodin is an anthraquinone present in fungal metabolites and constituent of rhubarb. 2-Hydroxyemodin proves to be mutagenic to Salmonella typhimurium TA1537 in the absence of activation system[1].
Product Specifications
CAS Number
[641-90-7]
UNSPSC
12352005
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-hydroxyemodin.html
Purity
99.74
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(C(C3=C1C=C(C)C(O)=C3O)=O)C(O)=CC(O)=C2
Molecular Formula
C15H10O6
Molecular Weight
286.24
References & Citations
[1]Masuda T, et al. 2-Hydroxyemodin, an active metabolite of emodin in the hepatic microsomes of rats. Mutat Res. 1985;149 (3) :327-332.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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