Tenovin-3
Product Specifications
UNSPSC Description
Tenovin-3 is a p53 activator[1][2].
Target Antigen
MDM-2/p53
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Tenovin-3.html
Purity
98.0
Solubility
DMSO : ≥ 31 mg/mL
Smiles
O=C(NC(NC1=CC=C(N)C=C1)=S)C2=CC=C(C(C)(C)C)C=C2
Molecular Weight
327.44
References & Citations
[1]Lain S, et al. Discovery, in vivo activity, and mechanism of action of a small-molecule p53 activator. Cancer Cell. 2008 May;13(5):454-63.|[2]Jifei Miao, et al. Nuclear HMGB1 promotes the phagocytic ability of macrophages. Exp Cell Res. 2020 Aug 1;393(1):112037.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19339/Tenovin-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19339/Tenovin-3-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1011301-27-1
Available Sizes
Curated Selection
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