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LH-RH (7-10)

LH-RH (7-10) is a tetrapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (7-10) produced in macrophages, type I-like and type II pneumocytes[3].

Product Specifications

CAS Number

38482-71-2

UNSPSC

12352209

Target

GnRH Receptor

Type

Peptides

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/lh-rh-7-10.html

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H](CCCNC(N)=N)C(N1[C@@H](CCC1)C(NCC(N)=O)=O)=O)[C@H](CC(C)C)N

Molecular Formula

C19H36N8O4

Molecular Weight

440.54

References & Citations

[1]Mandzhikyan, et al. Effect of luteinizing hormone releasing hormone fragments on the rat plasma kinin system. Russian. 1979; 69 (2) :115-118.|[2]Carlson JC, et al. The effect of LH-RH administration on LH release in the female rabbit. J Reprod Fertil. 1979 May;56 (1) :175-80. |[3]Yang X, et al. Enzymatic degradation of luteinizing hormone releasing hormone (LHRH) /[D-Ala6]-LHRH in lung pneumocytes. Pharm Res. 1998 Sep;15 (9) :1480-4. |[4]Talwar GP, et al. Bioeffective monoclonal antibody against the decapeptide gonadotropin-releasing hormone: reacting determinant and action on ovulation and estrus suppression. Proc Natl Acad Sci U S A. 1985 Feb;82 (4) :1228-31.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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