LH-RH (7-10)
LH-RH (7-10) is a tetrapeptide, one of major degradation products of luteinising-hormone releasing hormone (LHRH) via pituitary and hypothalamus. LH-RH (7-10) produced in macrophages, type I-like and type II pneumocytes[3].
Product Specifications
CAS Number
38482-71-2
UNSPSC
12352209
Target
GnRH Receptor
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/lh-rh-7-10.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CCCNC(N)=N)C(N1[C@@H](CCC1)C(NCC(N)=O)=O)=O)[C@H](CC(C)C)N
Molecular Formula
C19H36N8O4
Molecular Weight
440.54
References & Citations
[1]Mandzhikyan, et al. Effect of luteinizing hormone releasing hormone fragments on the rat plasma kinin system. Russian. 1979; 69 (2) :115-118.|[2]Carlson JC, et al. The effect of LH-RH administration on LH release in the female rabbit. J Reprod Fertil. 1979 May;56 (1) :175-80. |[3]Yang X, et al. Enzymatic degradation of luteinizing hormone releasing hormone (LHRH) /[D-Ala6]-LHRH in lung pneumocytes. Pharm Res. 1998 Sep;15 (9) :1480-4. |[4]Talwar GP, et al. Bioeffective monoclonal antibody against the decapeptide gonadotropin-releasing hormone: reacting determinant and action on ovulation and estrus suppression. Proc Natl Acad Sci U S A. 1985 Feb;82 (4) :1228-31.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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