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1-Aminohydantoin-13C3

1-Aminohydantoin-13C3 is 13C labeled 1-Aminohydantoin. 1-Aminohydantoin is a major metabolite of Nitrofurantoin (HY-A0090) in animal tissues and can be used as a standard for the determination of residues of veterinary agents in meat, milk et.al. 1-Aminohydantoin covalently binds to tissue proteins and is released from the tissues under slightly acidic conditions and derivatized with 2-nitrobenzaldehyde to form nitrophenyl derivatives of 1-Aminohydantoin before detection[1][2].

Product Specifications

CAS Number

957509-31-8

UNSPSC

12352005

Hazard Statement

H302

Target

Drug Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/1-aminoimidazolidine-2-4-dione-13c3.html

Solubility

10 mM in DMSO

Smiles

O=[13C]([13CH2]N1N)N[13C]1=O

Molecular Formula

13C3H5N3O2

Molecular Weight

118.07

Precautions

P264-P270-P330-P501

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Tao Le, et al. A fluorescent immunochromatographic strip test using a quantum dot-antibody probe for rapid and quantitative detection of 1-aminohydantoin in edible animal tissues. Anal Bioanal Chem. 2018 Jan;410 (2) :565-572. |[3]Yong Tang, et al. Development of a lateral flow immunoassay (LFA) strip for the rapid detection of 1-aminohydantoin in meat samples. J Food Sci. 2011 Aug;76 (6) :T138-43.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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