Ganglioside GD1b Disodium Salt (Bovine Brain)
Ganglioside GD1b Disodium Salt (Bovine Brain) (Disialoganglioside GD1b; Ganglioside C1) is an acidic glycosphingolipid containing two sialic acid residues linked to an internal galactose unit. Ganglioside GD1b Disodium Salt tightly packs with cholesterol to form lipid microdomains that modulate intracellular and intercellular signaling events. Concentrations of Ganglioside GD1b Disodium Salt (Bovine Brain) in the human brain increase with age and are positively correlated with pilocytic astrocytoma tumor grade. Ganglioside GD1b Disodium Salt has been detected in various other gliomas, including primitive neuroectodermal tumors, glioblastomas, and anaplastic astrocytomas.
Product Specifications
CAS Number
[19553-76-5]
Product Name Alternative
Disialoganglioside GD1b; Ganglioside C1; Ganglioside G2
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ganglioside-gd1b-disodium-salt-bovine-brain.html
Purity
98
Smiles
Molecular Formula
C84H146N4Na2O39
Molecular Weight
1882.04
Precautions
H315, H319, H335
References & Citations
[1]Kolter, et al. Ganglioside biochemistry. ISRN Biochem. 506160 (2012) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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