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BCN-PEG4-NHS ester

Product Specifications

UNSPSC Description

BCN-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. BCN-PEG4-NHS ester is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Target Antigen

ADC Linker; PROTAC Linkers

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related;PROTAC

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bcn-peg4-nhs-ester.html

Smiles

[H][C@@]12[C@@](CCC#CCC2)([H])[C@@H]1COC(NCCOCCOCCOCCOCCC(ON3C(CCC3=O)=O)=O)=O

Molecular Weight

538.59

References & Citations

[1]"An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. "

Shipping Conditions

Blue Ice

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-133439/BCN-PEG4-NHS-ester-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-133439/BCN-PEG4-NHS-ester-SDS-MedChemExpress.pdf

Available Sizes

Curated Selection

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