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Polydextrose

Polydextrose is an orally active prebiotic. Polydextrose promotes the growth of Pediococcus pentosaceus ATCC 43200. Polydextrose reduces cholesterol and synergistically lowers blood sugar with Sitagliptin. Currently, it is mainly used in the research of diseases such as hyperlipidemia, type 2 diabetes, and postoperative iron deficiency anemia[1][2][3][4][5].

Product Specifications

CAS Number

68424-04-4

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Bacterial

Type

Biochemical Assay Reagents

Related Pathways

Anti-infection

Field of Research

Infection; Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/polydextrose.html

Purity

95.0

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]1CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O.[n]

Molecular Formula

(C12H22O11) n

Precautions

H302, H315, H319, H335

References & Citations

[1]Pronczuk A, et al. Hypocholesterolemic effect of dietary polydextrose in gerbils and humans[J]. Nutrition Research, 2006, 26 (1) : 27-31.|[2]Mäkeläinen HS, et al. The effects of polydextrose and xylitol on microbial community and activity in a 4-stage colon simulator. J Food Sci. 2007 Jun;72 (5) :M153-9.|[3]Wanderley Porto MC, et al. Effect of Polydextrose on the Growth of Pediococcus pentosaceus as Well as Lactic Acid and Bacteriocin-like Inhibitory Substances (BLIS) Production. Microorganisms. 2022 Sep 24;10 (10) :1898.|[4]do Carmo MMR, et al. Intake of Polydextrose Alters Hematology and the Profile of Short Chain Fatty Acids in Partially Gastrectomized Rats. Nutrients. 2018 Jun 20;10 (6) :792.|[5]Stenman LK, et al. Probiotic B420 and prebiotic polydextrose improve efficacy of antidiabetic drugs in mice. Diabetol Metab Syndr. 2015 Sep 12;7:75.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

Phase 2

Available Sizes

Frequently Asked Questions

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