BIBB 515
Product Specifications
Product Name Alternative
UT-15-d9,UT-15-d7
UNSPSC Description
BIBB 515 is a potent, selective and orally active 2,3-oxidosqualene cyclase (OSC) inhibitor with ED50 values of 0.2-0.5 mg/kg and 0.36-33.3 mg/kg in rats and mice (1-5 hours), respectively. BIBB 515 exerts lipid-lowering effect mainly by inhibiting the production of low-density lipoprotein (LDL)[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/bibb-515.html
Purity
99.44
Solubility
DMSO : 2.5 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C=C1)Cl)N2CC/C(CC2)=C\C3=CC=C(C=C3)C4=NCCO4
Molecular Weight
380.87
References & Citations
[1]Eisele B, et al. Effects of a novel 2,3-oxidosqualene cyclase inhibitor on cholesterol biosynthesis and lipid metabolism in vivo. J Lipid Res. 1997 Mar;38(3):564-75.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116175/BIBB-515-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116175/BIBB-515-SDS-MedChemExpress.pdf
Clinical Information
Phase 1
CAS Number
156635-05-1
Available Sizes
Curated Selection
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